Burke’s research focuses on pediatric disaster preparedness and injury prevention. Her work includes evaluating gaps and identifying barriers in health and school systems to meet the needs of children, particularly those with access and functional needs, in a disaster. She is co-author of the book Landesman’s Public Health Management of Disasters and Associate Editor of Disaster Management and Public Health Preparedness. She is also the co-chair of the Los Angeles Children in Disasters Working Group and member of the Scientific Advisory Council for the American Red Cross.